A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/198 (2006.01)
Patent
CA 2574081
The subject invention pertains to methods of treating mental illnesses or conditions characterized by a decreased function of NMDA receptors and/or excessively enhanced glutamate release and activity of non-NMDA receptors (AMPA and/or kainate). Specifically disclosed are methods utilizing BrPhe, or isomers of analogs thereof, for treating or preventing mental illness or conditions such as schizophrenia.
Cette invention concerne des méthodes de traitement de maladies ou d'affections mentales qui se caractérisent par une fonction réduite des récepteurs NMDA et/ou une libération de glutamate et une activité excessivement renforcées de récepteurs non NMDA (AMPA et/ou kaïnate). Cette invention concerne spécifiquement des méthodes utilisant la BrPhe, ou des isomères ou analogues de celle-ci, pour le traitement ou la prévention de maladies ou d'affections mentales telles que la schizophrénie.
Dennis Donn M.
Glushakov Alexander V.
Gravenstein Nikolaus
Martynyuk Anatoly E.
Seubert Christoph
Gowling Lafleur Henderson Llp
University Of Florida Research Foundation Inc.
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