Methods and materials relating to leucine-rich repeat...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07H 21/04 (2006.01) C07K 5/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 9/16 (2006.01) C12N 9/64 (2006.01) C12N 15/66 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2399649

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted LRR protein-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from thymus (Hyseq clone identification numbers 16395938 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted LRR protein-like polypeptides, and antibodies specific for such polypeptides.

L'invention concerne des nouveaux polynucléotides et les polypeptides codés par ces derniers, ainsi que des mutants et des variants de ces derniers qui correspondent à un nouveau polypeptide humain sécrété du type protéine LRR. Ces polynucléotides comprennent des séquences d'acide nucléique isolées d'une banque d'ADNc du thymus (numéros d'identification de clone Hyseq 16395938) (SEQ ID NO: 1). D'autres aspects de l'invention concernent des vecteurs contenant des processus de production de nouveaux polypeptides humains sécrétés du type protéine LRR, et des anticorps spécifiques à ces polypeptides.

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