C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12N 5/00 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2561742
Provided herein are methods for identifying a risk of osteoarthritis in a subject, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating osteoarthritis, and therapeutic and preventative methods applicable to osteoarthritis. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
La présente invention a trait à des procédés permettant l'identification d'un risque d'ostéoarthrite chez un sujet, des réactifs et des trousses pour la mise en oeuvre des procédés, des procédés pour l'identification d'agents thérapeutiques candidats pour le traitement d'ostéoarthrite, et des procédés thérapeutiques et préventifs applicables à l'ostéoarthrite. Ces modes de réalisation reposent sur une analyse de variations polymorphes dans des séquences nucléotidiques au sein du génome humain.
Braun Andreas
Kammerer Stefan M.
Langdown Maria L.
Mah Steven
Nelson Matthew Roberts
Sequenom Inc.
Smart & Biggar
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