Methods for the treatment of neuronal atrophy-associated...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/00 (2006.01) A61K 38/00 (2006.01) A61K 38/43 (2006.01) A61K 39/395 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 9/14 (2006.01) C12N 9/64 (2006.01) C12N 15/85 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2372190

The invention features methods of diagnosis and treating a patient having Alzheimer's disease or other neuronal atrophy-associated dementia by determining or altering, respectively, the level of activity of pathways from the endoplasmic reticulum to lysosomes in the patient.

L'invention concerne des méthodes de diagnostic et de traitement d'un patient atteint de la maladie d'Alzheimer ou d'un autre type de démence neuronale associée à une atrophie, consistant à déterminer ou à modifier le niveau d'activité des voies du réticulum endoplasmique aux lysosomes du patient.

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