C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/22 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2562024
The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
La présente invention se rapporte à des méthodes et à des compositions permettant d'éviter ou de soulager la douleur associée au cancer des os, notamment la douleur liée au cancer et associée à une métastase osseuse, par administration d'un antagoniste du facteur de croissance neuronale (NGF). Cet antagoniste du NGF peut être un anticorps anti-NGF (du type anti-hNGF) qui a la possibilité de se lier à hNGF.
Mantyh Patrick William
Shelton David L.
Borden Ladner Gervais Llp
Regents Of The University Of Minnesota
Rinat Neuroscience Corp.
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