A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/5377 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01)
Patent
CA 2696807
Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1- b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt or solvate thereof, to human patients. Specifically, dosing, dosing schedules or dosing regimens are provided herein. Further, pharmaceutical formulations are provided. Methods of treating proliferative diseases or FLT-3 mediated diseases in humans are also provided.
L'invention porte sur des procédés consistant à administrer de la N-(5-tert-butyl-isoxazol-3-yl)- N'-{4-[7-(2-morpholin-4-yl-éthoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phényl}urée, ou un sel pharmaceutiquement acceptable ou solvate de celle-ci, à des patients humains. De façon spécifique, l'invention porte sur un dosage, des programmes de dosage ou des régimes de dosage. En outre, l'invention porte sur des formulations pharmaceutiques. L'invention porte sur des procédés de traitement de maladies prolifératives ou de maladies à médiation par FLT-3 chez des êtres humains.
Eichelberger Shawn R.
James Joyce K.
Savall Traci L.
Ambit Biosciences Corp.
Osler Hoskin & Harcourt Llp
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