Methods of diagnosis of cancer, compositions and methods of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/16 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2467433

Described herein are genes whose expression are up-regulated or down-regulated in specific cancers or other diseases, or are otherwise regulated in disease. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of these selected conditions.

Cette invention concerne des gènes dont l'expression est régulée positivement ou négativement dans certains cancers ou pathologies spécifiques, ou bien dont l'expression est régulée dans les états pathologiques. Sont également décrites des méthodes et des compositions connexes convenant pour le diagnostic, le pronostic et le traitement de ces pathologie ainsi que ces méthodes permettant d'identifier les modulateurs de ces dernières.

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