A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/40 (2006.01) A61K 9/00 (2006.01) A61K 9/12 (2006.01) A61K 9/16 (2006.01) A61K 9/72 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2296620
The present invention relates to pharmaceutical compositions for delivery of drugs intended to reside in the nose, compositions for nasal administration of drugs, e.g., antiviral agents, and particularly antiviral agents comprising the human major rhinovirus receptor, also known as intercellular adhesion molecule-1 (ICAM-1); to methods of making said nasal drug compositions, and to an improved process for the removal of residual solvent from pharmaceutical matrices.
L'invention concerne des compositions pharmaceutiques pour l'administration de médicaments destinés à résider dans le nez, et des compositions pour l'administration de médicaments par voie nasale, p. ex. d'agents antiviraux, et en particulier d'agents antiviraux comprenant le récepteur principal de rhinovirus humain, également connu sous le nom de molécule d'adhésion intercellulaire-1 (ICAM-1). L'invention concerne en outre des procédés de préparation pour ces compositions médicamenteuses administrées par voie nasale et un procédé amélioré pour éliminer le solvant résiduel des matrices pharmaceutiques.
Antonsen Kris P.
Caudle Margaret
Concessio Neville M.
Nayar Rajiv
Shearer Michael A.
Borden Ladner Gervais Llp
Corporation Bayer
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