Methods of screening nucleic acids using mass spectrometry

Details Methods of screening nucleic acids using mass spectrometry Methods of screening nucleic acids using mass spectrometry

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2248084

This invention relates to methods for screening nucleic acids for mutations by analyzing nonrandomly fragmented nucleic acids using mass spectrometric techniques and to procedures for improving mass resolution and mass accuracy of these methods of detecting mutations.

L'invention concerne des méthodes qui permettent de cribler des acides nucléiques à la recherche de mutations en analysant de manière non aléatoire des acides nucléiques fragmentés à l'aide de techniques de spectrométrie de masse, ainsi que des procédures permettant d'améliorer la résolution et la précision de masse de ces méthodes de détection de mutations.

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