A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4409 (2006.01) A61K 31/166 (2006.01)
Patent
CA 2600712
The present invention relates to compositions and methods of using peroxisome proliferator-activated receptor-gamma (PPAR.gamma.) antagonists. In one embodiment, the present invention relates to compositions and methods for preparing and using such antagonist compositions. In another embodiment, the present invention provides for using PPAR-gamma antagonist compositions to treat disease. such as cancer. In other embodiments, the present invention provides for using PPAR-gamma antagonist and one or more additional anti- cancer agent compositions to treat cancer.
L'invention concerne des compositions et des méthodes d'utilisation d'antagonistes du récepteur gamma activé proliférateur du péroxisome (PPAR-gamma). Dans un mode de réalisation, l'invention concerne des compositions et des méthodes pour préparer et pour utiliser de telles compositions d'antagonistes. Dans un autre mode de réalisation, l'invention concerne l'utilisation de compositions d'antagonistes de PPAR-gamma pour traiter des maladies, notamment un cancer. Dans encore d'autres modes de réalisation, l'invention concerne l'utilisation d'un antagoniste de PPAR-gamma et au moins une composition supplémentaire présentant un agent anticancéreux pour traiter le cancer.
Blumenthal Rosalyn
Burton Jack
Center For Molecular Medicine And Immunology
Immunomedics Inc.
Smart & Biggar
LandOfFree
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