C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 19/00 (2006.01) A61K 39/385 (2006.01) A61K 39/395 (2006.01) C07K 16/44 (2006.01) G01N 33/545 (2006.01) G01N 33/574 (2006.01) G01N 33/74 (2006.01)
Patent
CA 2090620
2090620 9204047 PCTABS00011 Methods for diagnosing pre-hypertension, hypertension, congestive cardiomyopathy, renal failure, salt-sensitivity and adenomas and endocrine cell hyperplasias are disclosed. Also disclosed are methods for monitoring hypertension therapy, congestive cardiomyopathy therapy, renal failure therapy and adenoma and endocrine cell hyperplasia therapy. These methods involve using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject. Additionally, methods for treating a hypertensive subject by inducing passive or active immunity to human ouabain in the subject are disclosed, along with an antibody having binding specificity for ouabain.
Blaustein Mordecai P.
Ducharme Donald W.
Fisher Jed F.
Hamlyn John M.
Harris Douglas W.
Sim & Mcburney
University Of Maryland At Baltimore
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