Methods of treatment of amyloidosis using aspartyl-protease...

A - Human Necessities – 61 – K

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A61K 31/165 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2553973

The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A- beta protein.

La présente invention a trait aux acétyl 2-hydroxy-1,3-diaminospirocyclohexanes et leurs dérivés qui sont utiles dans le traitement de maladies, troubles, et conditions associés à l'amyloïdose. L'amyloïdose désigne un groupe de maladies, troubles, et conditions associés au dépôt anormal de la protéine A-bêta.

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