Methods of using pnkp30, a member of the b7 family, to...

Details Methods of using pnkp30, a member of the b7 family, to... Methods of using pnkp30, a member of the b7 family, to...

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2606867

Novel methods of using isolated polypeptides, isolated polynucleotides encoding the polypeptides, and related compositions are disclosed for pNKp30 protein. The methods involved modulating the proliferation of T-cells in vitro and in vivo and modulation of immune response. The present invention also includes methods for producing pNKp30, including soluble molecules, uses therefor and antibodies thereto.

L'invention concerne de nouveaux procédés d'utilisation de polypeptides isolés, de polynucléotides isolés codant ces polypeptides, ainsi que de compositions associées pour la protéine pNKp30. Ces procédés consistent à moduler la prolifération de lymphocytes T in vitro et in vivo et à moduler la réponse immunitaire. L'invention concerne également des procédés de production de pNKp30, comprenant des molécules solubles, l'utilisation de celles-ci ainsi que des anticorps de celles-ci.

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