Microarrays of polypeptides

G - Physics – 01 – N

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G01N 33/68 (2006.01) B01J 19/00 (2006.01)

Patent

CA 2366123

Microarrays of polypeptides on a solid support are provided. The microarray compositions find use in the multiplexed detection and quantitation of ligands, e.g. antigens or antibodies, in a miniaturized format. The substrate is used for detecting binding of ligands to a plurality of polypeptides for screening and diagnostic purposes.

L'invention concerne des jeux ordonnés de microéchantillons sur un support solide. Les compositions de jeux ordonnés de microéchantillons trouvent leur utilisation dans la détection multiplexée et la quantification de ligands, par ex. d'antigènes ou d'anticorps, dans un format miniaturisé. Le substrat est utilisé pour détecter des liaisons de ligands à plusieurs polypeptides à des fins diagnostiques et de dépistage.

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