A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/52 (2006.01) A61K 38/27 (2006.01) A61K 38/28 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01) A61P 3/10 (2006.01) A61P 5/00 (2006.01)
Patent
CA 2715665
A microparticle, comprising an agglomerate of a hydrophilic active substance containing particle, which particle comprises an amphiphilic polymer composed of a hydrophobic segment of poly (hydroxy acid) and a hydrophilic segment of polysaccharides or polyethylene glycol, and a hydrophilic active substance, is characterized by an efficient inclusion of the hydrophilic active substance, and a release of the hydrophilic active substance at an appropriate speed in the human body, and is hence very useful as a DDS pharmaceutical preparation.
L'invention concerne des microparticules utiles en tant que préparations DDS. Les microparticules selon l'invention sont préparées en associant des polymères amphipatiques, constitués de segments poly(hydroxy acide) hydrophobes et de segments polysaccharide ou polyéthylène glycol hydrophiles, qui comprennent des particules contenant une substance active hydrophile fabriquées en incluant une substance active hydrophile, qui peuvent piéger efficacement la substance active hydrophile et qui peuvent libérer la substance active hydrophile dans le corps à une vitesse appropriée.
Hirano Taisuke
Ida Nobuo
Kakizawa Yoshinori
Koiwa Masakazu
Koshi Yoichiro
Smart & Biggar
Toray Industries Inc.
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