Mixture of primary fatty acids obtained from sugar cane wax

A - Human Necessities – 61 – K

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A61K 31/20 (2006.01) A61K 36/899 (2006.01) A61P 1/04 (2006.01) A61P 3/06 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2285242

A new natural mixture of primary fatty acids of high molecular weight ranging from 24 to 38 carbon atoms, especially those ranging between 26 and 36 carbon atoms and more especially those of straight chain of 26, 28, 29, 30, 31, 32, 33, 34, 35 and 36 carbon atoms. This mixture has a relative composition of each fatty acid that is highly reproducible batch to batch and it is extracted from sugar cane (Saccharum officinarum, L.) wax. This mixture of fatty acids has specific pharmacological properties that supports its use as an active component of pharmaceutical formulations used as hypocholesterolemic and against hypercholesterolaemia type II, as antiplatelet, anti-thrombotic and anti-ischemic. This mixture of primary fatty acids is also effective in the inhibition of the development of gastric ulcers induced by different agents.

L'invention concerne un nouveau mélange naturel d'acides gras primaires de haut poids moléculaire renfermant 24 à 38 atomes de carbone, notamment ceux renfermant 26 à 36 atomes de carbone et plus spécialement ceux ayant une chaîne droite constituée de 26, 28, 29, 30, 31, 32, 33, 34, 35 et 36 atomes de carbone. Ce mélange, qui a une composition relative des différents acides gras facile à reproduire de lot en lot, est extrait de la cire de la canne à sucre (Saccharum officinarum, L.). Il possède des propriétés pharmacologiques qui justifient son emploi comme principe actif dans des formulations pharmaceutiques utilisées comme hypocholestérolémiants et comme agents de lutte contre l'hypercholestérolémie de type II, comme agent antiplaquettaire, antithrombotique et anti-ischémique. Il est également efficace pour inhiber le développement d'ulcères gastriques induits par divers agents.

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