C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/34 (2006.01) A61K 31/70 (2006.01) C07H 21/02 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2093664
The present invention refers to an RNA molecule with catalytic activity comprising at least one modified nucleoside, wher- ein the hydroxy group at the 2'-position of the ribose sugar is replaced by a modifier group, selected from halo, sulfhydryl, azido, amino, monosubstituted amino and disubstituted amino groups, a process for the preparation of modified RNA molecules and the use of modified RNA molecules as therapeutic agents and biocatalysts.
Benseler Fritz
Eckstein Fritz
Heidenreich Olaf
Olsen David B.
Pieken Wolfgang A.
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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