C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61P 3/00 (2006.01)
Patent
CA 2699382
The present invention relates to modulators of ATP-B inding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
La présente invention concerne des modulateurs des transporteurs à ATP-Binding Cassette ('ABC') ou de fragments de ces derniers, y compris le régulateur de la conductance transmembranaire de la mucoviscidose, ou des compositions et des procédés à base de ces modulateurs. La présente invention a également pour objet des procédés de traitement de maladies médiées par un transporteur ABC à l'aide de tels modulateurs.
Binch Hayley
Fanning Lev T.d.
Grootenhuis Peter D.j.
Hadida Ruah Sara S.
Hazlewood Anna
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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