Modulators of dopamine neurotransmission

Details Modulators of dopamine neurotransmission Modulators of dopamine neurotransmission

C - Chemistry, Metallurgy

07

D

C07D 319/08 (2006.01) A61K 31/357 (2006.01) A61P 25/00 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2722986

The present invention relates to novel 1-(4H-1,3-benzodioxin-2-yl)methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically asdopaminergic stabilizers. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

L'invention concerne de nouveaux dérivés de 1-(4H-1,3-benzodioxine-2-yl)méthanamine servant de modulateurs de la neurotransmission de la dopamine et, plus précisément, de stabilisateurs dopaminergiques. Dans d'autres aspects, l'invention concerne l'utilisation de ces composés dans un procédé de thérapie, ainsi que des compositions pharmaceutiques renfermant ces composés.

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