C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/30 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) C07K 16/28 (2006.01) C12N 5/12 (2006.01) C12N 5/20 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2182369
The invention relates to monoclonal antibodies which specifically bind to the tumor rejection antigen precursor molecule MAGE-1, hybridomas which produce these monoclonal antibodies, and their use. Also described is a recombinant form of MAGE-1, peptides which are useful as immunogens, and immunogenic compositions containing the peptides and an adjuvant.
L'invention concerne des anticorps monoclonaux qui se fixent spécifiquement au précurseur de l'antigène permettant le rejet de tumeurs qu'est MAGE-1. L'invention concerne également des hybridomes qui produisent ces anticorps monoclonaux et leur utilisation. On décrit également une forme de MAGE-1 obtenue par recombinaison, des peptides qui sont utiles en tant qu'immunogènes et des compositions immunogènes contenant les peptides et un adjuvant.
Boon-Falleur Thierry
Chen Yachi
Chen Yao-Tseng
Garin-Chesa Pilar
Old Lloyd J.
Ludwig Institute For Cancer Research
Memorial Sloan-Kettering Cancer Center
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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