C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/37, 195/1.10
C12N 5/02 (2006.01) A61K 39/395 (2006.01) C07K 16/30 (2006.01) G01N 33/577 (2006.01)
Patent
CA 1215917
Abstract A panel of monoclonal antibodies, produced from human bladder tumors as immunogen, is used to diagnose the presence of transitional cell carcinoma in patients. The panel is also used to identify and differentiate low grade non-invasive papillomas from invasive life-threatening transitional cell carcinomas, thereby enabling decisions as to the extent of bladder surgery. These mAbs can also be used as a panel for tissue typing of normal and abnormal cell specimens.
449320
Cordon-Cardo Carlos
Fradet Yves
Lloyd Kenneth O.
Melamed Myron R.
Old Lloyd J.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Sloan-Kettering Institute For Cancer Research
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