Monoclonal antibody for immunologically analyzing or...

Details Monoclonal antibody for immunologically analyzing or... Monoclonal antibody for immunologically analyzing or...

C - Chemistry, Metallurgy

12

N

C12N 15/06 (2006.01) C07K 16/44 (2006.01) C12N 5/20 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2321195

A hybridoma which produces a monoclonal antibody against an endocrine disrupting substance or its degradation product obtained by fusing spleen cells or lymphoid cells of an animal having been immunized with a complex of the endocrine disrupting substance or a compound similar thereto with a protein with myeloma cells; the monoclonal antibody produced thereby; and a method for immunologically detecting the endocrine disrupting substance or its degradation product and a method for immunologically concentrating the same each by using the above antibody.

L'invention concerne un hybridome produisant un anticorps monoclonal contre une substance de rupture de l'endocrine ou ses produits de dégradation, obtenu par fusion de cellules de la rate ou de cellules lymphoïdes d'un animal ayant été immunisées par un complexe de la substance de rupture de l'endocrine ou d'un composé similaire avec une protéine et des cellules myélomes. L'invention concerne en outre l'anticorps monoclonal ainsi produit, un procédé pour la détection immunologique de la substance de rupture de l'endocrine, ainsi qu'un procédé pour la concentration immunologique de cette substance, chacun de ces procédés utilisant l'anticorps précité.

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