Morpholine derivative

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 265/30 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2155183

1. A morpholine derivative represented by formula (I) or a pharmaceutically acceptable salt thereof: Image (I) wherein R1 and R3, which may be the same or different, each represent a hydrogen atom or a lower alkyl group; R2 represents a halogen atom; and the dotted line indicates an optional double bond. These compounds exhibit a selective 5-HT reincorporation inhibitory activity and a selective 5-HT2 receptor antagonistic activity and useful as a therapeutic agent for depression, anxiety, etc. with reduced side effects.

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