C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2333853
prflated MUC nucleic acids are provided which correspond to a Mucin gene located on human chromosome 7q22, or on a mammalian chromosome structurally or functionally equivalent thereto, which Mucin gene is normally predominantly expressed in the colon. Also provided are diagnostic and therapeutic uses of isolated MUC nucleic acids, MUC polypeptides encoded thereby and anti-MUC mAb.
L'invention concerne des acides nucléiques de MUC isolés correspondant à un gène Mucine situé sur le chromosome humain 7q22, ou sur un chromosome de mammalien structurellement ou fonctionnellement équivalent, ce gène Mucine étant normalement principalement exprimé dans le côlon. L'invention concerne également les utilisations diagnostiques et thérapeutiques d'acides nucléiques de MUC isolés, des polypeptides de MUC codés par ces acides nucléiques et des mAb anti-MUC.
Antalis Toni Marie
Gotley David Charles
Mcguckin Michael Andrew
Williams Stephanie Jane
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Corporation Of The Trustees Of The Order Of The Sisters Of M
The Council Of The Queensland Institute Of Medical Research
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