Multi-arm polymeric conjugates of...

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 65/333 (2006.01) A61K 47/48 (2006.01) A61P 35/04 (2006.01) A61K 31/4745 (2006.01)

Patent

CA 2640013

A four arm-polyethylene glycol-7-ethyl-l0-hydroxycamptothecin conjugate, such as Formula (I), is disclosed. Methods of making the conjugates and methods of treating mammals using the same are also disclosed.

L'invention un conjugué de polyéthylène glycol-7-éthyl-l0-hydroxycamptothécine à quatre bras, tel que représenté par formule (I). L'invention concerne également des procédés de fabrication desdits conjugués, ainsi que des méthodes de traitement de mammifères à l'aide de ceux-ci.

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