C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12N 9/12 (2006.01) C12N 15/09 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2357011
Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of predetermined nucleic acid target sequences using a multiplex assay format. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, genotyping, medical marker diagnostics, and the like.
L'invention concerne des procédés utilisant la dépolymérisation d'un hybride d'acide nucléique pour analyser qualitativement et quantitativement la présence de séquences cibles d'acides nucléiques prédéterminées au moyen d'une méthode de dosage multiplex. Les applications de ces procédés comprennent la détection de polymorphismes de nucléotides simples, l'identification de changements de bases simples, la spéciation, le génotypage, les diagnostics de marqueurs médicaux, et les applications associées.
Andrews Christine Ann
Gu Trent
Hartnett James R.
Kephart Daniel
Leippe Donna
Fetherstonhaugh & Co.
Promega Corporation
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