C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C07H 21/00 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2497740
The invention provides methods and processes for the identification of polymorphisms at one or more designated sites, without interference from non- designated sites located within proximity of such designated sites. Probes are provided capable of interrogation of such designated sites in order to determine the composition of each such designated site. By the methods of this invention, one or more mutations within the CFTR gene and the HLA gene complex can be identified.
La présente invention concerne des procédés pour identifier des polymorphismes en un ou plusieurs sites désignés, sans interférence de sites non désignés, situés à proximité desdits sites désignés. Des sondes permettent d'interroger de tels sites désignés, afin de déterminer la composition de chacun des sites désignés. Ces procédés permettent d'identifier une ou plusieurs mutations dans le gène CFTR et dans le complexe génique HLA.
Hashmi Ghazala
Li Alice Xiang
Seul Michael
Bioarray Solutions Ltd.
Borden Ladner Gervais Llp
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