N-11 truncated amyloid-beta monoclonal antibodies,...

Details N-11 truncated amyloid-beta monoclonal antibodies,... N-11 truncated amyloid-beta monoclonal antibodies,...

C - Chemistry, Metallurgy

12

N

C12N 5/18 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2498058

This invention relates to antibodies, including specified portions or variants, specific for at least the human Amyloid-beta 11 N-terminal site, i.e. A.szlig.11-x peptides. It further provides methods of making and using said antibodies, including therapeutic formulations, administration and devices.

L'invention concerne des anticorps, y compris des parties spécifiées ou des variantes génétiques, qui sont spécifiques au moins pour le site N-terminal bêta-amyloïde 11 humain, à savoir les peptides A.szlig.11-x. Elle concerne en outre des procédés de fabrication et d'utilisation de ces anticorps, y compris des formulations thérapeutiques, des modes d'administration et des dispositifs.

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