N-(2-thiazolyl)-amide derivatives as gsk-3 inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/41 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2650323

The present invention relates to the use of N- (2-thiazolyl) -amide derivatives of formula (I) for the treatment and/or prophylaxis of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, especially neurodegenerative diseases, such as Alzheimer's disease, or non-insulin dependent diabetes mellitus.

La présente invention concerne l'utilisation de dérivés de N-(2-thiazolyl)-amides représentés par la formule (I) pour le traitement et/ou la prévention d'une maladie induite par la glycogène synthase kinase 3 (GSK-3), en particulier des maladies neurodégénératives, telles que la maladie d'Alzheimer ou le diabète non insulinodépendant.

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