C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/182 (2006.01) A61K 31/495 (2006.01) C07D 295/185 (2006.01) C07D 295/192 (2006.01) C07D 317/68 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2172913
An N-acylpiperazine derivative or a salt thereof in accordance with the present invention is represented by the following formula 1: wherein R1 represents a lower alkyl, hydroxy lower alkyl, lower acyl, or arylcarbonyloxy lower alkyl group; R2 represents hydrogen atom or a lower alkyl, lower alkoxy, lower alkenyl, amino, or nitro group; R3 and R4, which are identical to or different from each other, represent hydrogen atoms, halogen atoms, or cyano, nitro, lower alkyl, or lower alkoxy groups; and n represents 0 or 1. The N-acylpiperazine derivative has anti-ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulsers.
Fukunishi Hirotada
Kobayashi Koji
Kojima Nao
Nishino Chikao
Sato Fumitaka
Gowling Lafleur Henderson Llp
Shiseido Co. Ltd.
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