C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/58 (2006.01) A61K 31/135 (2006.01) A61K 31/40 (2006.01) C07C 217/74 (2006.01) C07D 209/16 (2006.01) C07D 209/58 (2006.01) C07D 213/38 (2006.01)
Patent
CA 2346363
.beta.-Aminotetralin derivatives of formula (I) which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing a .beta.-aminotetralin derivative as the active ingredient are described. The .beta.-aminotetralins are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.
L'invention concerne des dérivés de .beta.-aminotétraline de formule (I), qui sont des ligands du récepteur Y Y5 (NPY5) du neuropeptide, leurs procédés de préparation, ainsi que des compositions pharmaceutiques contenant un dérivé de .beta.-aminotétraline comme principe actif. Les .beta.-aminotétralines servent au traitement de troubles et de maladies liées au sous-type Y5 du récepteur NPY.
Baxter Ellen W.
Carson John R.
Dax Scott L.
Lovenberg Timothy W.
Ludovici Donald W.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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