N-benzyl, n' -arylcarbonylpiperazine derivatives as lxr...

Details N-benzyl, n' -arylcarbonylpiperazine derivatives as lxr... N-benzyl, n' -arylcarbonylpiperazine derivatives as lxr...

C - Chemistry, Metallurgy

07

D

C07D 241/04 (2006.01) A61K 31/4965 (2006.01) A61K 31/497 (2006.01) A61P 9/10 (2006.01) C07D 243/08 (2006.01) C07D 261/14 (2006.01) C07D 295/192 (2006.01) C07D 307/14 (2006.01) C07D 307/52 (2006.01) C07D 307/66 (2006.01) C07D 309/14 (2006.01) C07D 317/58 (2006.01) C07D 333/20 (2006.01) C07D 333/48 (2006.01)

Patent

CA 2694604

The present invention relates to N-benzyl,N'-arylcarbonylpiperazine derivatives having the general Formula (I) to pharmaceutical compositions comprising the same, and to the use of a these N- benzyl,N'-arylcarbonylpiperazine derivatives for the manufacture of a medicament for treating or preventing atherosclerosis and related disorders associated with cholesterol and bile acids transport and metabolism.

La présente invention porte sur des dérivés de N-benzyl, N'-arylcarbonylpipérazine représentés par la formule générale I, sur des compositions pharmaceutiques les comprenant, et sur l'utilisation de ces dérivés de N-benzyl, N'-arylcarbonylpipérazine pour la fabrication d'un médicament destiné à traiter ou prévenir l'athérosclérose et des maladies apparentées associées au transport et au métabolisme du cholestérol et des acides biliaires.

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