N-biaryl and n-arylheteroaryl 2-substituted piperazine...

Details N-biaryl and n-arylheteroaryl 2-substituted piperazine... N-biaryl and n-arylheteroaryl 2-substituted piperazine...

C - Chemistry, Metallurgy

07

D

C07D 295/06 (2006.01) A61K 31/495 (2006.01) A61K 31/501 (2006.01) A61K 31/506 (2006.01) A61P 3/04 (2006.01) A61P 15/10 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07D 213/38 (2006.01) C07D 213/74 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01)

Patent

CA 2588567

The present invention relates to certain N-biaryl and N-arylheteroaryl 2- substituted piperazine derivatives of Formula (Ia) that are modulators of the 5HT2C receptor. Accordingly, compounds of the present invention are useful for the treatment of 5HT2C receptor associated diseases or disorders, such as, obesity, Alzheimer Disease, erectile dysfunction and related disorders.

La présente invention concerne certains dérivés de pipérazine 2-substitués de N-biaryle et de N-arylhétéroaryle de formule (Ia) utilisés comme modulateurs du récepteur 5HT2C. Les composés de l'invention sont utiles pour le traitement de troubles ou de maladies associés au récepteur 5HT2C, tels que l'obésité, la maladie d'Alzheimer, la dysérection et les troubles apparentés.

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