N-carbacycle monosubstituted indolocarbazoles as protein...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/14 (2006.01) A61K 31/404 (2006.01) A61P 3/10 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2467780

This invention relates to N-carbacycle monosubstituted indolocarbazole compounds. Furthermore, this invention relates to medicaments comprising N- carbacycle monosubstituted indolocarbazoles compounds and the use of such compounds for treating non-insulin dependent diabetes mellitus, acute stroke and other neurotraumatic injuries, for treating diabetes mellitus, as a chemotherapeutic for the treatment of various malignant diseases, for treating diseases caused by malfunctioning of specific signaling pathways, and for treating neurodegenerative diseases such as for example Alzheimer's disease.

Cette invention se rapporte à des composés indolocarbazoles monosubstitués à N-carbacycles, ainsi qu'à des médicaments comprenant des composés indolocarbazoles monosubstitués à N-carbacycles et à l'utilisation de ces composés pour traiter le diabète sucré non insulinodépendant, les attaques aiguës et d'autres traumatismes neurologiques, pour traiter le diabète sucré, comme agent chimiothérapeutique pour traiter diverses affections malignes, pour traiter des maladies causées par un dysfonctionnement des voies de signalisation spécifiques et pour traiter les maladies neurodégénératives telles que la maladie d'Alzheimer.

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