N-hydroxyamide derivatives and use thereof

Details N-hydroxyamide derivatives and use thereof N-hydroxyamide derivatives and use thereof

C - Chemistry, Metallurgy

07

D

C07D 241/04 (2006.01) A61K 31/495 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 15/06 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2630551

The present invention is related to N-hydroxyamide derivatives of Formula (I) and use thereof in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.

La présente invention concerne des dérivés de N-hydroxamides de Formule (I) et leurs applications, en particulier dans le traitement prophylactique et/ou thérapeutique de troubles auto-immuns, de maladies inflammatoires, de maladies cardio-vasculaires, de maladies neurodégénératives, de cancers, de maladies respiratoires et de fibroses, y compris la sclérose en plaques, l'arthrite, l'emphysème, la bronchopneumopathie chronique obstructive, la fibrose hépatique et la fibrose pulmonaire.

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