N-oxide and/or di-n-oxide derivatives of dopamine receptor...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/94 (2006.01) A61K 31/451 (2006.01) A61P 25/06 (2006.01) A61P 25/14 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2683719

The invention relates to N-oxide and/or di-N-oxide derivatives of dopamine receptor stabilizers/modulators having the general formula (1) or (2) and pharmaceutical preparations containing the said compounds. Further, the invention relates the use of the said compounds for the treatment of a disorder in the central nervous system, and particularly for the treatment of dopamine mediated disorders such as e.g. movement disorders, psychoses, anxiety disorders, neurodevelopmental disorders, sleep disorders and substance related disorders.

L'invention concerne des dérivés N-oxyde et di-N-oxyde de stabilisateurs/modulateurs des récepteurs de la dopamine représentés par la formule générale (1) ou (2) et des préparations pharmaceutiques contenant lesdits composés. En outre, l'invention concerne l'utilisation desdits composés pour le traitement d'un trouble du système nerveux central et, en particulier, pour le traitement de troubles à médiation dopaminergique tels que, par exemple, les troubles du mouvement, les psychoses, les troubles anxieux, les troubles du développement neurologique, les troubles du sommeil et les troubles liés à des substances.

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