N-oxides of 4,5-epoxy-morphinanium analogs

Details N-oxides of 4,5-epoxy-morphinanium analogs N-oxides of 4,5-epoxy-morphinanium analogs

C - Chemistry, Metallurgy

07

D

C07D 489/08 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2670342

Novel N-oxides of 4,5-epoxy-morphinanium analogs are disclosed. Pharmaceutical compositions containing the N-oxides of 4,5-epoxy-morphinanium analogs and methods of their pharmaceutical uses are also disclosed. The compounds disclosed are useful, inter alia, as modulators of opioid receptors.

La présente invention concerne de nouveaux N-oxydes d'analogues 4,5-époxy-morphinanium. La présente invention concerne également des compositions pharmaceutiques contenant les N-oxydes d'analogues 4,5-époxy-morphinanium et leurs procédés d'utilisations pharmaceutiques. Les composés décrits sont utiles, entre autres, en tant que modulateurs de récepteurs opioïdes.

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