C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/38 (2006.01)
Patent
CA 2637027
The present invention relates to anN-(phosphonoalkyl)-amino acid, a related compound or a derivative thereof, the N-(phos.rho.honoalkyl)-amino acid, related compound or derivative thereof being in a form as a free acid, salt, partial salt, lactone, amide or ester, or in stereoisomeric or non- stereoisomeric form, other than N-(phosphonomethyl)-glycine or N,N- bis(phosphonomethyl)- glycine. Also included is a composition including an N- (phosphonoalkyl)-amino acid, a related compound or a derivative thereof in a form as a free acid, salt, partial salt, lactone, amide or ester, or in stereoisomeric or non-stereoisomeric form, and a cosmetically or pharmaceutically acceptable vehicle for topical or systemic administration to a mammalian subject, as well as a method of administering an effective amount of such a composition for alleviating or improving a condition, disorder, symptom or syndrome associated with at least one of a nervous, vascular, musculoskeletal or cutaneous system.
La présente invention concerne un acide N-(phosphonoalkyl)-aminé, un composé apparenté ou un dérivé de celui-ci, l~acide N-(phosphonoalkyl)-aminé, le composé apparenté ou le dérivé de celui-ci étant sous forme d~acide libre, de sel, de sel partiel, de lactone, d~amide ou d~ester ou bien sous forme stéréo-isomère ou non stéréo-isomère autre que la N-(phosphonométhyl)-glycine ou N,N-bis(phosphonométhyl)-glycine. L~invention concerne également une composition comprenant un acide N-(phosphonoalkyl)-aminé, un composé apparenté ou un dérivé de celui-ci sous forme d~acide libre, de sel, de sel partiel, de lactone, d~amide ou d~ester ou bien sous forme stéréo-isomère ou non stéréo-isomère et un excipient acceptable du point de vue cosmétique ou pharmaceutique pour l~administration topique ou systémique à un sujet mammifère, ainsi qu~un procédé d~administration d~une quantité efficace d~une telle composition pour atténuer ou améliorer une maladie, un désordre, un symptôme ou un syndrome associé à au moins l~un des systèmes nerveux, vasculaire, musculosquelettique ou cutané.
Van Scott Eugene J.
Yu Ruey J.
Gowling Lafleur Henderson Llp
Van Scott Eugene J.
Yu Ruey J.
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