N-triazolyl-2-indolecarboxamides and their use as cck-a...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 403/12 (2006.01) A61K 31/41 (2006.01) C07D 249/14 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2289573

The invention concerns compounds of formula (I) in which R¿1?, R¿4?, X¿1?, X¿2?, X¿3?, X¿4?, Y¿1?, Y¿2? and Y¿3? are as defined in claim 1. These compounds have partial or total agonist activity of CCK-A receptors and are useful for treating eating problems, obesity, tardive dyskinesia and disorders of the gastrointestinal sphere.

L'invention a pour objet des composés de formule (I) dans laquelle R1, R4, X1, X2, X3, X4, Y1, Y2 et Y3 sont tels que définis à la revendication 1. Ces composés possédent une activité agoniste partielle ou totale des récepteurs CCK-A, et sont utiles dans le traitement des désordres alimentaires, de l'obésité, de la dyskinésie tardive et des troubles de la sphère gastrointestinale.

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