Naphtalenic aminoalkyl derivatives, the acid addition salts...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/00 (2006.01) C07C 29/147 (2006.01) C07C 59/84 (2006.01) C07C 59/88 (2006.01) C07C 63/44 (2006.01) C07C 63/72 (2006.01) C07D 295/03 (2006.01) C07D 295/145 (2006.01) C07D 307/34 (2006.01)

Patent

CA 1210391

Title : "New naphtalenic aminoalkyl derivatives, the acid addition salts thereof and the process for preparing same, as well as the application in therapeutics of these derivatives and salts" (Invention of Alain-René SCHOOFS, Guy BOURGERY, Bernard BUCHER) Applicant : DELALANDE S.A. ABSTRACT OF THE DISCLOSURE New naphtalenic aminoalkyl derivatives corresponding to the for- mula : Image (I) in which : - R1 and R2 are identical or different and represent a hydrogen atom or an alkyl group comprising 1 to 4 carbon atoms or form, conjointly with the nitrogen atom to which they are linked, a heterocyclic radical chosen from the following : pyrrolidino, piperidino, hexamethyleneimino, morpholino, piperazino, 4-methyl piperazino ; - n = 1, 2 or 3 ; - R represent a hydrogen or halogen atom or a methyl group; and - R3 represents a hydrogen or halogen atom or a methyl or methoxy group, as well as the organic or mineral acid addition salts thereof. These derivatives and salts are usable in therapeutics, more particularly as antidepressants and/or analgesics.

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