Neisseria genomic sequences and methods of their use

Details Neisseria genomic sequences and methods of their use Neisseria genomic sequences and methods of their use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07K 14/22 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2371032

The invention provides methods of obtaining immunogenic proteins from genomic sequences including Neisseria, including the amino acid sequences and the corresponding nucleotide sequences, as well as the genomic sequence of Neisseria meningitidis B. The proteins so obtained are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.

L'invention se rapporte à des procédés d'obtention de protéines immunogéniques dérivées de séquences génomiques incluant Neisseria, incluant les séquences d'acides aminés et les séquences nucléotidiques correspondantes, ainsi que la séquence génomique de Neisseria meningitidis B. Les protéines ainsi obtenues s'avèrent utiles en tant qu'antigènes destinés à la production de vaccins et de compositions immunogéniques et/ou à des fins diagnostiques.

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