Nematicidal pyrazoles

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 409/04 (2006.01) A01N 43/56 (2006.01) A01N 47/16 (2006.01) A01N 47/38 (2006.01) A61K 31/4155 (2006.01) A61P 33/10 (2006.01) C07D 333/16 (2006.01) C07D 333/22 (2006.01)

Patent

CA 2339970

Novel pyrazoles of formula (I) wherein R1 represents halogen, C1-6 alkyl, C1-5 haloalkyl, C2-6 alkoxy, C1-4 alkylthio, C2-5 alkenyloxy, C3-5 alkynyloxy, C2-6 (total carbon number) alkoxyalkyl), C2-6 (total carbon number) alkylthioalkyl, C1-5 haloalkoxy, C2-6 (total carbon number) alkoxyalkoxy, hydroxy or optionally substituted phenyl, R2 represents hydrogen, halogen, C1-5 alkyl, C2-6 (total carbon number) alkoxyalkyl, C2-6 (total carbon number) alkylthioalkyl, C2-6 (total carbon number) alkylsulfinylalkyl, C2-6 (total carbon number) alkylsulfonylalkyl or C1-5 haloalkyl, R3 represents hydrogen, C1-5 alkyl, - COR4, COOR5, CH(OR6)2 or CH2Si(R7)3, R4 represents C1-10 alkyl, C1-6 haloalkyl, C2-6 alkenyl, optionally substituted C3-6 cycloalkyl, C2-6 (total carbon number) alkoxyalkyl, C22-6 (total carbon number) alkylthioalkyl, optionally substituted phenyl, C1-6 haloalkyl, alkylamino, di- (C1-6 alkyl)amino or optionally substituted phenylamino, R5 represents C1-7 alkyl, R6 and R7 represent C1-6 alkyl, and n is 1, 2 or 3, and when n is 2 or 3, the corresponding number (n) of R1 radicals may be the same or different, processes for preparing these compounds and their use as nematicides and anthelmintics.

L'invention concerne de nouveaux pyrazoles correspondant à la formule (I) dans laquelle R<1> représente halogène, alkyle C1-6, haloalkyle C1-5, alcoxy C2-6, alkylthio C1-4, alcényloxy C2-5, alkynyloxy C3-5, alcoxyalkyle C1-6 (nombre carbone total), alkylthioalkyle C2-6 (nombre carbone total), haloalcoxy C1-5, alcoxyalcoxy C2-6 (nombre carbone total), hydroxy ou phényle éventuellement substitué; R<2> représente hydrogène, halogène, alkyle C1-5, alcoxyalkyle C2-6 (nombre carbone total), alkylthioalkyle C2-6 (nombre carbone total), alkylsulfinylalkyle C2-6 (nombre carbone total), alkylsulfonylalkyle C2-6 (nombre carbone total) ou haloalkyle C1-5, R<3> représente hydrogène, alkyle C1-5, -COR<4>, -COOR<5>, CH(OR<6>)2 ou CH2Si(R<7>)3, R<4> représente alkyle C1-10, haloalkyle C1-6, alcényle C2-6, cycloalkyle C3-6 éventuellement substitué, alcoxyalkyle C2-6 (nombre carbone total), alkylthioalkyle C2-6 (nombre carbone total), phényle éventuellement substitué, haloalkyle C1-6, alkylamino, di(C1-6 alkyle)amino ou phénylamino éventuellement substitué, R<5> représente alkyle C1-7, R<6> et R<7> représentent alkyle C1-6, et n représente 1, 2 et 3, n étant 2 ou 3, le nombre correspondant (n) de radicaux R<1> pouvant être identique ou différent. L'invention concerne également des procédés de préparation de ces composés et leur utilisation comme nématicides et antihelminthiques.

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