Neurogenesis by muscarinic receptor modulation

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/00 (2006.01) A61K 31/325 (2006.01) A61K 31/445 (2006.01) A61K 31/473 (2006.01) A61K 31/66 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2620333

The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on muscarinic receptor modulation, such as via inhibition of acetylcholine esterase (AChE) activity, alone or in combination with another neurogenic agent to stimulate or activate the formation of new nerve cells.

L'invention concerne des procédés destinés à traiter des maladies et des troubles du système nerveux central et périphérique par stimulation ou augmentation de la neurogénèse. Cette invention concerne également des compositions et des procédés basés sur la modulation du récepteur muscarinique, notamment par inhibition de l'activité de l'acétylchorine estérase (AChE), seule ou en combinaison avec un autre agent neurogène afin de stimuler ou d'activer la formation de nouvelles cellules nerveuses.

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