Neutralizing human anti-igfr antibody

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2484000

The present invention includes fully human, neutralizing, monoclonal antibodies against human Insulin-like Growth Factor Receptor-I (IGFR1). The antibodies are useful for treating or preventing cancer in a subject. Also included are methods of using and producing the antibodies of the invention.

La présente invention concerne des anticorps monoclonaux neutralisants entièrement humains dirigés contre le récepteur humain du facteur de croissance de type insuline I (IGFR1). Ces anticorps sont utiles pour traiter ou prévenir un cancer chez un sujet. L'invention concerne également des méthodes d'utilisation et de production de ces anticorps.

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