Neutrokine-alpha and neutrokine-alpha splice variant

Details Neutrokine-alpha and neutrokine-alpha splice variant Neutrokine-alpha and neutrokine-alpha splice variant

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 35/04 (2006.01) C07K 14/52 (2006.01) C12N 1/02 (2006.01) C12N 15/70 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2476675

The present invention relates to nucleic acid molecules encoding Neutrokine- alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain. Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies or portions thereof that specifically bind Neutrokine-alpha and/or Neutrokine-alphaSV and diagnostic and therapeutic methods using these antibodies. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders using the compositions of the invention.

L'invention se rapporte à des molécules d'acide nucléique codant Neutrokine-alpha et/ou des polypeptides de Neutrokine-alphaSV, et contenant des formes solubles du domaine extracellulaire. L'invention concerne aussi Neutrokine-alpha et/ou des polypeptides de Neutrokine-alphaSV, ainsi que vecteurs, des cellules hôtes et des procédés recombinants de fabrication correspondants. Cette invention a également trait à des anticorps ou à des portions d'anticorps qui se lient de manière spécifique à Neutrokine-alpha et/ou à Neutrokine-alphaSV, ainsi qu'à des procédés diagnostiques et thérapeutiques utilisant ces anticorps. L'invention se rapporte aussi à des procédés diagnostiques de détection de troubles liés au système immunitaire et à des procédés thérapeutiques de traitement de troubles liés au système immunitaire au moyen des compositions selon l'invention.

Affiliated with

Also associated with

Rating

Neutrokine-alpha and neutrokine-alpha splice variant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Neutrokine-alpha and neutrokine-alpha splice variant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neutrokine-alpha and neutrokine-alpha splice variant will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1832087