C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/527 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 25/06 (2006.01) C07D 471/10 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2705599
The invention relates to novel CGRP antagonists of general formulas (Ia) and (Ib) in which R1, R2, R3, R4, and R5 are defined as indicated below, the tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures, and salts thereof, and the hydrates of the salts, especially the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing said compounds, the use thereof, and methods for the production thereof.
La présente invention concerne de nouveaux antagonistes de CGRP de formules générales (Ia) et (Ib) dans lesquelles R1, R2, R3, R4 et R5 sont tels que définis ci-après, ainsi que les tautomères, isomères, diastéréoisomères, énantiomères, hydrates, mélanges et sels de ceux-ci, ainsi que les hydrates des sels de ceux-ci, notamment leurs sels physiologiquement compatibles avec des acides ou des bases inorganiques ou organiques, des médicaments contenant ces composés, leur utilisation et des procédés de production de ceux-ci.
Dahmann Georg
Doods Henri
Gottschling Dirk
Heimann Annekatrin
Mueller Stephan Georg
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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