C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/90 (2006.01) C07D 207/416 (2006.01)
Patent
CA 2536608
Use of a derivative of an optically active maleimide of the general formula (VII): (see formula VII) wherein: A represents: (i) H or straight-chain or branched alkyl having up to 8 carbon atoms, or (ii) phenyl or benzyl which are optionally up to trisubstituted by identical or different substituents selected from the group consisting of hydroxyl, nitro, a halogen atom, cyano, carboxyl, trifluoromethyl, trifluoromethoxy, straight-chain or branched alkoxy having up to 6 carbon atoms and a group of the general formula: -NR6R7 or -SO2R8, wherein: R6 and R7 are identical or different and represent H, phenyl or straight-chain or branched alkyl having up to 5 carbon atoms, and R8 represents straight-chain or branched alkyl having up to 4 carbon atoms or phenyl, in the preparation of the diastereomerically pure 1,4-dihydropyridines of the general formulae (IVa) and (IVb): (see formulae IVa and IVb) wherein: A is as defined above; R1 represents: (i) straight-chain or branched alkyl having up to 8 carbon atoms which is optionally substituted by straight-chain or branched alkoxy having up to 6 carbon atoms or hydroxyl, or (ii) cycloalkyl having 3 to 7 carbon atoms; and R2 represents the radical (see formula I) wherein R4 and R5 are identical or different and represent: (i) a halogen atom, cyano, ethinyl, trifluoromethoxy, methylthio, nitro or trifluoromethyl, or (ii) straight-chain or branched alkyl, alkenyl, alkinyl or alkoxy having up to 4 carbon atoms, and one of the substituents optionally represents H; and a salt thereof.
Fey Peter
Junge Bodo
Kaulen Johannes
Meier Heinrich
Mittendorf Joachim
Aktiengesellschaft Bayer
Bayer Schering Pharma Aktiengesellschaft
Fetherstonhaugh & Co.
LandOfFree
New highly selective process for the preparation of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with New highly selective process for the preparation of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and New highly selective process for the preparation of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1564277