C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 3/10 (2006.01) C07D 221/00 (2006.01) C07D 231/00 (2006.01) C07D 235/00 (2006.01) C07D 237/00 (2006.01) C07D 471/00 (2006.01) C07D 471/04 (2006.01) C07D 498/00 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2529729
The invention relates to substituted imidazo-pyridinones and imidazo- pyridazinones of general formula (I), wherein Y and R1 to R4 are defined as indicated in claim 1, the tautomers, enantiomers, diastereomers, mixtures, and salts thereof that have valuable pharmacological properties, especially an inhibiting effect on the activity of the dipeptidyl peptidase IV (DPP-IV) enzyme.
Imidazo-pyridinones et imidazo-pyridazinones de formule générale (I) dans laquelle Y ainsi que R1 à R4 sont tels que définis dans la revendication 1. La présente invention concerne les tautomères, les énantiomères, les diastéréomères desdites substances, leurs mélanges et leurs sels. Ces substances possèdent des propriétés pharmacologiques précieuses, en particulier un effet inhibiteur sur l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).
Eckhardt Matthias
Hauel Norbert
Himmelsbach Frank
Kauffmann-Hefner Iris
Langkopf Elke
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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