New modulating molecules for an improved regulated...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/63 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2683907

The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease.

L'invention concerne un système d'expression amélioré assurant l'expression régulée d'une molécule thérapeutique codée à protéine ou à acide nucléique dans les cellules d'un sujet, utilisé dans le traitement de maladies. Plus particulièrement, elle concerne un système d'expression génétique régulée amélioré, des compositions pharmaceutiques et leurs utilisations dans le traitement de maladies.

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