New npy antagonists

Details New npy antagonists New npy antagonists

C - Chemistry, Metallurgy

07

C

C07C 279/14 (2006.01) A61K 31/155 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2303528

There is provided pharmaceutically useful compounds of formula (I), wherein Ar1, R1, R2, R3, R4, R5 and R6 have meanings given in the description, which are useful as antagonists of neuropeptide Y and in particular in the treatment of cardiovascular diseases, for example vasoconstriction.

L'invention se rapporte à de nouveaux composés pharmaceutiquement utiles et représentés par la formule (I), dans laquelle Ar?1¿, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ possèdent les significations données dans le descriptif de l'invention. Ces composés s'avèrent utiles en tant qu'antagonistes du neuropeptide Y et servent notamment à traiter les maladies cardio-vasculaires, telles que la vasoconstriction.

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